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Article

An initiator codon mutation in SDE2 causes recessive embryonic lethality in Holstein cattle.

Journal of dairy science - 1 Jul 2018

Fritz Sébastien, Hoze Chris, Rebours Emmanuelle, Barbat Anne, Bizard Méline, Chamberlain Amanda, Escouflaire Clémentine, Vander Jagt Christy, Boussaha Mekki, Grohs Cécile, Allais-Bonnet Aurélie, Philippe Maëlle, Vallée Amélie, Amigues Yves, Hayes Benjamin J, Boichard Didier, Capitan Aurélien

Abstract excerpt

Researching depletions in homozygous genotypes for specific haplotypes among the large cohorts of animals genotyped for genomic selection is a very efficient strategy to map recessive lethal mutations. In this study, by analyzing real or imputed Illumina BovineSNP50 (Illumina Inc., San Diego, CA) genotypes from more than 250,000 Holstein animals, we identified a new locus called HH6 showing significant negative...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 29680649
DOI: 10.3168/jds.2017-14119

Genes

SDE2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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