Article

Mitochondrial protein interaction landscape of SS-31

2019-08-18

Abstract excerpt

Mitochondrial dysfunction underlies the etiology of a broad spectrum of diseases including heart disease, cancer, neurodegenerative diseases, and the general aging process. Therapeutics that restore healthy mitochondrial function hold promise for treatment of these conditions. The synthetic tetrapeptide, elamipretide (SS-31), improves mitochondrial function, but mechanistic details of its pharmacological effects a...

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Literature Corpus work: 3bef9e6a-d5a0-59a4-b5b5-1edfd74d8b27
DOI: 10.1101/739128

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