Article

Targeting high-density aromatic peptides to cardiolipin optimizes the mitochondrial membrane potential

2023-09-28

Abstract excerpt

<h4>ABSTRACT</h4> The mitochondrial membrane potential (ΔΨm) is created by the accumulation of protons on an outer leaflet of the inner mitochondrial membrane and drives the synthesis of most cellular ATP, which is essential for cellular bioenergetics and survival. The ΔΨm also facilitates the electrogenic transport of cations, such as Ca 2+ , and regulates generation of reactive oxygen species, which serves as...

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Literature Corpus work: b604d4a9-75f9-5899-b4e5-dcca88120205
DOI: 10.1101/2023.09.28.560027

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