Article

SS-31 Reverses Mitochondrial Fragmentation in Fibroblasts from Patients with DCMA, a Mitochondrial Cardiomyopathy

2019-06-17

Abstract excerpt

<h4>ABSTRACT</h4> <h4>Objectives</h4> We used patient dermal fibroblasts to characterize the mitochondrial abnormalities associated with the dilated cardiomyopathy with ataxia syndrome (DCMA) and to study the effect of the mitochondrially-targeted peptide SS-31 as a potential novel therapeutic. <h4>Background</h4> DCMA is an understudied autosomal recessive disorder thought to be related to Barth syndrome but c...

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Literature Corpus work: 49c9171d-f849-540a-9b22-f7fe115236ff
DOI: 10.1101/672857

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