Article

Early life stress-induced miR-708-5p regulates mood disorder-associated behavioural phenotypes in mice and is a potential diagnostic biomarker for bipolar disorder

2024-03-14

Abstract excerpt

Mood-disorders (MDs) are caused by a complex interplay of genetic and environmental (GxE) risk factors. However, the molecular pathways engaged by GxE risk factors to trigger specific MD-associated endophenotypes are still poorly understood. Here, by using unbiased small RNA sequencing in peripheral blood mononuclear cells (PBMCs), we identified the BD-associated miR-708-5p as one of the most strongly upregulated...

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Literature Corpus work: 3bc9bcf2-5746-5322-a7c3-2d3f6893879f
DOI: 10.1101/2024.03.14.584977

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