Article
Aripiprazole, but Not Olanzapine, Alters the Response to Oxida-Tive Stress, Reducing the Activation of Mitogen-Activated Protein Kinases (MAPKs) and Promoting Cell Survival in FAO Cells
2024-07-02
Abstract excerpt
Chronic administration of atypical antipsychotics (AAPs) is commonly associated with in-creased cardiovascular disease load. Although the increase in weight gain and related dis-ease risk is generally considered the main contributing factor, direct interference with mi-tochondrial bioenergetics, particularly in the liver, where these drugs are catabolized, is emerging as an additional relevant contributor to metab...
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Identifiers and source
- Literature Corpus work
- 3b9c24fb-69db-5538-a96f-3e0e469ac151
- DOI
- 10.20944/preprints202407.0129.v1
