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Aripiprazole, but Not Olanzapine, Alters the Response to Oxida-Tive Stress, Reducing the Activation of Mitogen-Activated Protein Kinases (MAPKs) and Promoting Cell Survival in FAO Cells

2024-07-02

Abstract excerpt

Chronic administration of atypical antipsychotics (AAPs) is commonly associated with in-creased cardiovascular disease load. Although the increase in weight gain and related dis-ease risk is generally considered the main contributing factor, direct interference with mi-tochondrial bioenergetics, particularly in the liver, where these drugs are catabolized, is emerging as an additional relevant contributor to metab...

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Literature Corpus work
3b9c24fb-69db-5538-a96f-3e0e469ac151
DOI
10.20944/preprints202407.0129.v1
Open publication

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Aripiprazole, but Not Olanzapine, Alters the Response to Oxida-Tive Stress, Reducing the Activation of Mitogen-Activated Protein Kinases (MAPKs) and Promoting Cell Survival in FAO CellsDOI 10.20944/preprints202407.0129.v1
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