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Article

Energy metabolism adaptations and gene expression reprogramming in a cellular MAFLD model

2021-11-09

Abstract excerpt

Mitochondrial dysfunction plays a critical role in metabolic associated fatty liver disease (MAFLD). This study aims to characterize mitochondrial dysfunctions in a human MAFLD Huh7 cell model triggered by free fatty acid (FFA) (palmitate and oleate) overload for 24 hours. We investigate its impact on cellular energy metabolism and identify potential targets for MAFLD treatment. FFA-treated cells displayed an accu...

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Literature Corpus work
4f0487f2-7809-5f9d-aec7-f4a4be691c40
DOI
10.1101/2021.11.08.467719
Open publication

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Energy metabolism adaptations and gene expression reprogramming in a cellular MAFLD modelDOI 10.1101/2021.11.08.467719
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