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Metabolic Syndrome and Antipsychotics: The Role of Mitochondrial Fission/Fusion Imbalance

23 Apr 2018

Abstract excerpt

Second-generation antipsychotics (SGAs) are known to increase cardiovascular risk through several physiological mechanisms, including insulin resistance, hepatic steatosis, hyperphagia, and accelerated weight gain. There are limited prophylactic interventions to prevent these side effects of SGAs, in part because the molecular mechanisms underlying SGAs toxicity are not yet completely elucidated. In this...

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PMID: 29740394
DOI: 10.3389/fendo.2018.00144

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