Article

LncRNA <i>Dnmt3aos</i> regulates <i>Dnmt3a</i> expression leading to aberrant DNA methylation in macrophage polarization

2019-01-07

Abstract excerpt

Long non-coding RNAs (lncRNAs) play key roles in various biological processes. However, the roles of lncRNAs in macrophage polarization remain largely unexplored. In this study, thousands of lncRNAs were identified that are differentially expressed in distinct polarized bone marrow-derived macrophages (BMDMs). Among them, Dnmt3aos (DNA methyltransferase 3A, opposite strand), as a known lncRNA, locates on the anti...

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Literature Corpus work: 3b781093-beee-5382-95b9-ad822e10ca5b
DOI: 10.1101/514307

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