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Epigenetic regulation of macrophage activation in chronic obstructive pulmonary disease

14 Aug 2024

Abstract excerpt

Macrophages in the innate immune system play a vital role in various lung diseases such as asthma, chronic obstructive pulmonary disease (COPD), acute lung injury and pulmonary fibrosis. Macrophages involved in the process of immunity need to go through a process of activation, including changes in gene expression and cell metabolism. Epigenetic modifications are key factors of macrophage activation including DNA...

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PMID: 39206196
DOI: 10.3389/fimmu.2024.1445372

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