Article

Transgenic production of the mouse in vitro- and in vivo-derived embryos: Effect on the methylation pattern of OCT4 promoter, expression levels of Dnmts, and Oct4

2024-08-14

Abstract excerpt

<title>Abstract</title> We examined the methylation pattern of OCT4 promotor and expression levels of <italic>Dnmts</italic> and <italic>Oct4</italic> genes in the transgenic mouse embryos obtained by in vivo and in vitro experiments. A gene construct consisting of selected parts of the region upstream from the human OCT4 promoter and enhanced green fluorescent protein as a reporter (OCT4-EGFP) was used for pr...

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Literature Corpus work: 3b72ac04-9463-5389-bb0c-27a7ed5f2122
DOI: 10.21203/rs.3.rs-4767253/v1

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