Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

An efficient strategy for generation of transgenic mice by lentiviral transduction of male germline stem cells in vivo

1 Dec 2015

Abstract excerpt

BACKGROUND: Male germline stem cells (MGSCs) are a subpopulation of germ cells in the testis tissue. MGSCs are capable of differentiation into spermatozoa and thus are perfect targets for genomic manipulation to generate transgenic animals. METHOD: The present study was to optimize a protocol of production of transgenic mice through transduction of MGSCs in vivo using lentiviral-based vectors. The recombinant...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Animal Genetics and Reproduction
Share to Pluripotent Stem Cells Research
Share to Sperm and Testicular Function

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 26705472
DOI: 10.1186/s40104-015-0058-4

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

An efficient strategy for generation of transgenic mice by lentiviral transduction of male germline stem cells in vivoPMID 26705472Read ↗

Efficient Generation of Transgenic Rats Through the Male Germline Using Lentiviral Transduction and Transplantation of Spermatogonial Stem CellsSemantic proximity Read ↗

Characterization of Immortalized Dairy Goat Male Germline Stem Cells (mGSCs)Semantic proximity Read ↗

Production of transgenic mice by random recombination of targeted genes in female germline stem cellsSemantic proximity Read ↗

Generation of a novel germline stem cell line expressing a germline-specific reporter in the mouse.Semantic proximity Read ↗

Pluripotent Male Germline Stem Cells from Goat Fetal Testis and Their Survival in Mouse TestisSemantic proximity Read ↗

DDX4-EGFP transgenic rat model for the study of germline development and spermatogenesis †Semantic proximity Read ↗

Germline Stem Cell Transplantation and TransgenesisSemantic proximity Read ↗

An oocyte-specific Cas9-expressing mouse for germline CRISPR/Cas9-mediated genome editing.Semantic proximity Read ↗

Generation and Application of Male Mice with Specific Expression of Green Fluorescent Protein in Germ Cells.Semantic proximity Read ↗

Transgenesis and Genome Editing of Mouse Spermatogonial Stem Cells by Lentivirus Pseudotyped with Sendai Virus F Protein.Semantic proximity Read ↗

Non-viral transfection of goat germline stem cells by nucleofection results in production of transgenic sperm after germ cell transplantation.Semantic proximity Read ↗

Germ cell transplantation into mouse testes procedure.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.