Article
Dynamic regulation of DNA methyltransferases in human oocytes and preimplantation embryos after assisted reproductive technologies
3 Jul 2014
Abstract excerpt
DNA methylation is a key epigenetic modification which is essential for normal embryonic development. Major epigenetic reprogramming takes place during gametogenesis and in the early embryo; the complex DNA methylation patterns are established and maintained by DNA methyltransferases (DNMTs). However, the influence of assisted reproductive technologies (ART) on DNA methylation reprogramming enzymes has...
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