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Article

The joint detection of CEA and ctDNA in cerebrospinal fluid: an auxiliary tool for the diagnosis of leptomeningeal metastases in cancer.

Journal of cancer research and clinical oncology - 1 May 2023

Wang Yong, Luo Ningning, Gao Ye, Wu Yaqing, Qin Xueting, Qi Yingxue, Sun Tingting, Tao Rongjie, Qi Chuang, Liu Baoyan, Yuan Shuanghu

Abstract excerpt

BACKGROUND: Leptomeningeal metastases (LMs) are highly invasive which leads to poor prognosis, but the accurate diagnosis of LM is challenging. It is necessary to investigate more advanced diagnostic methods to realize precision medicine. The main purpose of this study was to select a more effective method for the auxiliary diagnosis of LM by comparing various detection methods. The secondary purpose was to...

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PMID: 35583828
DOI: 10.1007/s00432-022-04053-7

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