Article
Expression profile of sphingosine kinase 1 isoforms in human cancer tissues and cells: importance and clinical relevance of the neglected 1b-isoform
2022-10-17
Abstract excerpt
<h4>Introduction: </h4> Overexpression of sphingosine kinase 1 (SphK1) is casually associated with many types of cancer and inhibitors of SphK1 sensitize tumors to chemotherapy. SphK1 is expressed as two major isoforms, SphK1a and SphK1b. To date, no information has been reported on the SphK1 isoform expression profile and its clinical relevance. The purpose of this study was to examine the expression profile of t...
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Identifiers and source
- Literature Corpus work
- 3b57789c-915e-5fd3-8d35-51e55899f2ac
- DOI
- 10.21203/rs.3.rs-2156531/v1