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Article

Implication of Ceramide Kinase/C1P in Cancer Development and Progression

4 Jan 2022

Abstract excerpt

Cancer cells rewire their metabolic programs to favor biological processes that promote cell survival, proliferation, and dissemination. Among this relevant reprogramming, sphingolipid metabolism provides metabolites that can favor or oppose these hallmarks of cancer. The sphingolipid ceramide 1-phosphate (C1P) and the enzyme responsible for its biosynthesis, ceramide kinase (CERK), are well established...

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PMID: 35008391
DOI: 10.3390/cancers14010227

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