Article

Cardiac function and ECM morphology are altered with high fat diets in <i>Drosophila</i>

2023-08-09

Abstract excerpt

Cardiovascular disease is characterized by aberrant and excessive extracellular matrix (ECM) remodelling, termed fibrosis. Fibrotic remodelling is typically triggered by inflammation, which occurs systemically in obesity. Despite the contribution of fibrosis to adverse clinical outcomes and disease progression, there are no available treatments for this condition. Developing therapeutics for chronic conditions req...

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Literature Corpus work: 3b32332f-37f3-5816-bf9f-5890ccd70d8f
DOI: 10.1101/2023.08.08.552539

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