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Article

Lipotoxicity and cardiac dysfunction in mammals and<i>Drosophila</i>

19 Aug 2011

Abstract excerpt

The lipotoxic effects of obesity are important contributing factors in cancer, diabetes, and cardiovascular disease (CVD), but the genetic mechanisms, by which lipotoxicity influences the initiation and progression of CVD are poorly understood. Hearts, of obese and diabetic individuals, exhibit several phenotypes in common, including ventricular remodeling, prolonged QT intervals, enhanced frequency of diastolic...

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Share to Adipose Tissue and Metabolism
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Identifiers

PMID: 21851295
DOI: 10.3109/10409238.2011.599830

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