Article
Clonal hematopoiesis and inflammation in the vasculature: CHIVE, a prospective, longitudinal clonal hematopoiesis cohort and biorepository.
Blood advances - 9 Jul 2024
Shannon Morgan L, Heimlich J Brett, Olson Sydney, Debevec Ariana, Copeland Zachary, Kishtagari Ashwin, Vlasschaert Caitlyn, Snider Christina, Silver Alexander J, Brown Donovan, Spaulding Travis, Bhatta Manasa, Pugh Kelly, Stockton Shannon S, Ulloa Jessica, Xu Yaomin, Baljevic Muhamed, Moslehi Javid, Jahangir Eiman, Ferrell P Brent, Slosky David, Bick Alexander G, Savona Michael R
Abstract excerpt
ABSTRACT: Clonal hematopoiesis (CH) is an age-associated phenomenon leading to an increased risk of both hematologic malignancy and nonmalignant organ dysfunction. Increasingly available genetic testing has made the incidental discovery of CH clinically common yet evidence-based guidelines and effective management strategies to prevent adverse CH health outcomes are lacking. To address this gap, the prospective...
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