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Article

Clonal hematopoiesis, aging, and cardiovascular diseases.

Experimental hematology - 1 Mar 2020

Pardali Evangelia, Dimmeler Stefanie, Zeiher Andreas M, Rieger Michael A

Abstract excerpt

Cardiovascular diseases (CVDs) remain the leading cause of death worldwide. Many studies have provided evidence that both genetic and environmental factors induce atherosclerosis, leading thus to cardiovascular complications. Atherosclerosis is an inflammatory disease, and aging is strongly associated with the development of atherosclerosis. Recent experimental evidence suggests that clonal hematopoiesis (CH) is...

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Age Factors
Aging
Atherosclerosis
Clonal Evolution
Heart Failure
Hematopoiesis

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PMID: 31891750
DOI: 10.1016/j.exphem.2019.12.006

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