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Integrated analysis of single-cell and bulk RNA sequencing data reveals a CD8+ T cells signature predicting prognosis and immunotherapy response in hepatocellular carcinoma

2023-09-06

Abstract excerpt

<h4>Background: </h4> As we know, immune infiltration play an important role in tumor initiation and progression. Therefore, we devoted to exploring the effect of dynamic evolution of CD8 + T cells on hepatocellular carcinoma (HCC) progression. <h4>Methods: </h4> We comprehensively analyzed gene expression and clinical information in 2,423 HCC cells and 837 HCC samples. Seurat and Monocle algorithms were used to i...

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Literature Corpus work
3b09a262-7ce6-55a0-b348-60b91fe5afa9
DOI
10.21203/rs.3.rs-3319618/v1
Open publication

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Integrated analysis of single-cell and bulk RNA sequencing data reveals a CD8+ T cells signature predicting prognosis and immunotherapy response in hepatocellular carcinomaDOI 10.21203/rs.3.rs-3319618/v1
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