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Development and validation of a six-gene T cell-derived prognostic signature based on single-cell transcriptomics for hepatocellular carcinoma

2026-08-10

Abstract excerpt

<title>Abstract</title> <p>Background Hepatocellular carcinoma (HCC) exhibits pronounced heterogeneity. Existing prognostic models often lack an immunological perspective. This study leveraged single-cell transcriptomics to characterize T-cell features, constructing and validating a biologically interpretable prognostic model to enhance precise risk stratification in HCC. Methods Single-cell RNA-seq data from 6...

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Literature Corpus work
14fd5a39-ba02-534c-9d65-46fbfee1a81f
DOI
10.21203/rs.3.rs-10346961/v1
Open publication

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Development and validation of a six-gene T cell-derived prognostic signature based on single-cell transcriptomics for hepatocellular carcinomaDOI 10.21203/rs.3.rs-10346961/v1
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