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Identification of the CD8+T-cell exhaustion signature of Hepatocellular Carcinoma for the Prediction of prognosis and Immune microenvironment by Integrated Analysis of Bulk- and Single-Cell RNA Sequencing Data

2023-10-23

Abstract excerpt

<h4>Background: </h4> Hepatocellular carcinoma (HCC) is a prevalent type of cancer with high incidence and mortality rates. It is the third most common cause of cancer-related deaths. CD8+ T cell exhaustion (TEX) is a progressive decline in T cell function due to sustained T cell receptor stimulation from continuous antigen exposure. Studies have shown that CD8+ TEX plays an important role in the anti-tumor immune...

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Literature Corpus work
5f3166fe-17b8-5d53-8390-7a44017edc75
DOI
10.21203/rs.3.rs-3469033/v1
Open publication

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Identification of the CD8+T-cell exhaustion signature of Hepatocellular Carcinoma for the Prediction of prognosis and Immune microenvironment by Integrated Analysis of Bulk- and Single-Cell RNA Sequencing DataDOI 10.21203/rs.3.rs-3469033/v1
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