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Construction of CD8+ T cell-associated risk signature in hepatocellular carcinoma based on single-cell RNA-seq and bulk RNA-seq data

2023-06-06

Abstract excerpt

<title>Abstract</title> <p>Background Hepatocellular carcinoma (HCC) is the most prevalent form of primary liver cancer, characterized by high recurrence and mortality rates. Specific CD8<sup>+</sup> T cells have a central role in pathogenesis of HCC by recognizing and destroying tumor cells. Method Common CD8 + T cell signatures were obtained from bulk RNA-seq and scRNA-seq analysis. Univariate Cox regression,...

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Literature Corpus work
eebcf359-7f4b-54f8-9e95-385333a164fd
DOI
10.21203/rs.3.rs-2990692/v1
Open publication

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