Article
A novel panel based on immune infiltration and tumor mutational burden for prognostic prediction in hepatocellular carcinoma.
Aging - 10 Mar 2021
Xie Chan, Wu Hewei, Pan Tao, Zheng Xingrong, Yang Xiaoan, Zhang Genglin, Lian Yunwen, Lin Jiaxin, Peng Liang
Abstract excerpt
Tumor mutation burden (TMB) has been associated with prognosis in various malignancies, but it has yet to be elucidated in hepatocellular carcinoma (HCC). We aimed to investigate the prognostic effects of TMB and its relationship with immune infiltration through multiple databases and whole-exome sequencing, so as to establish a panel model capable of predicting prognosis. The results demonstrated that the...
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