Article

immgenT: A Comprehensive Reference of Convergent T-cell States in the Mouse

2026-02-02

Abstract excerpt

The immgenT collaborative project generated a comprehensive molecular atlas of T cells spanning virtually all mouse organs and disease states, profiling ∼800,000 cells from 750 samples with RNA, 128-plex surface protein, and αβTCR sequence. Applying a deep generative model to joint RNA and protein data defined the landscape of T-cell states organized into eight lineages and 107 robust clusters, integrating similar...

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Literature Corpus work: 3af09b3f-8487-5c0a-aabe-4319942deae8
DOI: 10.64898/2026.01.30.702892

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