Article

Novel therapy for gastric cancer peritoneal dissemination using genetically modified dental pulp cells and astatine-211

2025-10-15

Abstract excerpt

<h4>SUMMARY</h4> Peritoneal dissemination of gastric cancer is a terminal stage with limited treatment options and a five-year survival rate below 10%. To develop a more effective treatment, we created a new approach that uses genetically engineered human dental pulp cells (DPCs) that express the sodium/iodide symporter (NIS). These cells (NIS-DPCs) deliver astatine-211 (At-211) directly to tumor sites. When inje...

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Literature Corpus work: 3aeb0a9c-f000-5305-a6ac-e5867110ef80
DOI: 10.1101/2025.10.15.682497

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