Article
A tissue-engineered gastric cancer model for mechanistic study of anti-tumor drugs.
Biomedical materials (Bristol, England) - 1 Aug 2013
Gao Ming, Cai Yiting, Wu Wei, Shi Yazhou, Fei Zhewei
Abstract excerpt
The use of the traditional xenograft subcutaneous tumor model has been contested because of its limitations, such as a slow tumorigenesis, inconsistent chemotherapeutic results, etc. In light of these challenges, we aim to revamp the traditional model by employing an electrospun scaffold composed of polydioxanone, gelatin and elastin to boost the tumorigenesis. The scaffold featured a highly porous microstructure...
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