Article

Towards Effective CAIX-targeted Radionuclide and Checkpoint Inhibition Combination Therapy for Advanced Clear Cell Renal Cell Carcinoma

2024-02-21

Abstract excerpt

<h4>ABSTRACT</h4> <h4>Background</h4> Immune checkpoint inhibitors (ICI) are routinely used in advanced clear cell renal cell carcinoma (ccRCC). However, a substantial group of patients does not respond to ICI therapy. Radiation is a promising approach to increase ICI response rates since it can generate anti-tumor immunity. Targeted radionuclide therapy (TRT) is a systemic radiation treatment, ideally suited fo...

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Literature Corpus work: f3fec8ab-7576-5690-8a5a-a142fb565256
DOI: 10.1101/2024.02.16.580614

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