Article
Can molecular profiling enhance radiotherapy? Impact of personalized targeted gold nanoparticles on radiosensitivity and imaging of adenoid cystic carcinoma.
Theranostics - 1 Jan 2017
Hazkani Inbal, Motiei Menachem, Betzer Oshra, Sadan Tamar, Bragilovski Dimitri, Lubimov Leon, Mizrachi Aviram, Hadar Tuvia, Levi Mattan, Ben-Aharon Irit, Haviv Izhack, Popovtzer Rachela, Popovtzer Aron
Abstract excerpt
Personalized molecular profiling has an established role in selection of treatment for metastatic disease; however, its role in improving radiosensitivity and functional imaging has not been evaluated. In the current study, we examined molecular profiling as a tool for designing personalized targeted gold nanoparticles (GNP) to serve as dual-modal tumor radiosensitizers and functional imaging enhancers. To this...
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