Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

A Novel Approach for Image-Guided 131I Therapy of Pancreatic Ductal Adenocarcinoma Using Mesenchymal Stem Cell-Mediated NIS Gene Delivery

17 Sept 2018

Abstract excerpt

Abstract The sodium iodide symporter (SLC5A5/NIS) as theranostic gene would allow for non-invasive imaging of functional NIS expression and therapeutic radioiodine application. Genetically engineered mesenchymal stem cells (MSC), based on their tumor-homing abilities, show great promise as tumor-selective NIS gene delivery vehicles for non-thyroidal tumors. As a next step towards clinical application, tumor...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cancer Research and Treatments
Share to Pancreatic and Hepatic Oncology Research
Share to Renal and related cancers

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 30224540
DOI: 10.1158/1541-7786.mcr-18-0185

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

A Novel Approach for Image-Guided 131I Therapy of Pancreatic Ductal Adenocarcinoma Using Mesenchymal Stem Cell-Mediated NIS Gene DeliveryPMID 30224540Read ↗

The sodium iodide symporter (NIS): novel applications for radionuclide imaging and treatmentSemantic proximity Read ↗

The Biology of the Sodium Iodide Symporter and its Potential for Targeted Gene DeliverySemantic proximity Read ↗

Sodium Iodide Symporter for Nuclear Molecular Imaging and Gene Therapy: From Bedside to Bench and BackSemantic proximity Read ↗

In vivo imaging and tumor therapy with the sodium iodide symporterSemantic proximity Read ↗

Selective epithelial expression of <i>KRAS</i> <sup>G12D</sup> mutation drives ductal pancreatic neoplasia in OncopigsSemantic proximity Read ↗

Visualization of stem cell activity in pancreatic cancer expansion by direct lineage tracing with live imagingSemantic proximity Read ↗

Improved lentiviral transduction of human mesenchymal stem cells for therapeutic intervention in pancreatic cancerSemantic proximity Read ↗

Efficient Gene Delivery and Expression in Pancreas and Pancreatic Tumors by Capsid-Optimized AAV8 VectorsSemantic proximity Read ↗

Novel therapy for gastric cancer peritoneal dissemination using genetically modified dental pulp cells and astatine-211Semantic proximity Read ↗

Pancreatic cancer induced by in vivo electroporation-enhanced sleeping beauty transposon gene delivery system in mouse.Semantic proximity Read ↗

Human sodium/iodide symporter-mediated radioiodine gene therapy enhances the killing activities of CTLs in a mouse tumor model.Semantic proximity Read ↗

Image-Guided Mesenchymal Stem Cell Sodium Iodide Symporter (NIS) Radionucleotide Therapy for GlioblastomaSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.