Article

KLF14 Inhibits Renal Mesangial Cell Proliferation by Promoting Btg2 Gene Expression

2021-01-13

Abstract excerpt

Krüppel-like factor 14 is one of zinc finger protein family that are closely associated with regulation of transcription, and its function in the kidneys remains unclear. So KLF14-deficient mouse models were established using TALEN. The levels of blood cholesterol, HDL-C, LDL-C, and TGs were significantly decreased in KLF14-/- mice. KLF14-/- mice had more obvious mesangial cell proliferation and greater accumulati...

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Literature Corpus work: 3ad2fb8e-c687-574e-8eef-8f53c95e8ebf
DOI: 10.21203/rs.3.rs-122817/v1

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