Article
Signaling pathways of PAX2 and its role in renal interstitial fibrosis and glomerulosclerosis.
Journal of receptor and signal transduction research - 1 Dec 2012
Zhou Tian-Biao
Abstract excerpt
PAX2, a nuclear transcription factor in renal development, is strongly expressed during kidney development and plays an important role in kidney development, differentiation, and renal cell proliferation. PAX2 is expressed in epithelial cells of fetal kidneys and its expression is up-regulated in certain pathologic conditions. However, the transcription activation of PAX2 and its signaling pathways are...
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