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Article

Role of Krüppel-Like Factor 4 and its Binding Proteins in Vascular Disease

1 Jan 2014

Abstract excerpt

Krüppel-like factor 4(KLF4) is a zinc-finger transcription factor that plays a key role in cellular differentiation and proliferation during normal development and in various diseases, such as cancer. The results of recent studies have revealed that KLF4 is expressed in multiple vascular cell types, including phenotypically modulated smooth muscle cells(SMCs), endothelial cells and monocytes/macrophages and...

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PMID: 24573018
DOI: 10.5551/jat.23044

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