Article
Assessment of the evolutionary consequence of putative driver mutations in colorectal cancer with spatial multiomic data
2021-07-14
Abstract excerpt
Cancer genomic medicine relies on targeting driver genes. However, current catalogues of cancer drivers are mostly based on indirect measurements of mutation frequencies, positions or types, rather than their effect on clonal expansions in vivo . Moreover, non-genetic drivers are largely unknown, as are the epigenetic and transcriptomic effects of genetic drivers. Here we perform spatial computational inference o...
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Identifiers and source
- Literature Corpus work
- 3acd4d0c-72a0-5479-91f0-ccdafef4f72c
- DOI
- 10.1101/2021.07.14.451265