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Single-cell sequencing reveals the mechanisms of multiple myeloma progression: clarity or confusion?

1 Feb 2025

Abstract excerpt

Multiple myeloma (MM), the second most common hematologic malignancy, is characterized by the clonal expansion of myeloma cells and accumulation of genetic lesions. MM progression is accompanied by increased aggressiveness and drug resistance. Even the goal of "cure" remains hard to reach for most patients, advances in diagnosis and treatment have allowed some to achieve durable remissions and transition to...

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PMID: 39918600
DOI: 10.1007/s00277-025-06241-0

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