Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Shared and Unique Features of Human Interferon-Beta and Interferon-Alpha Subtypes

19 Jan 2021

Abstract excerpt

Type I interferons (IFN-I) were first discovered as an antiviral factor by Isaacs and Lindenmann in 1957, but they are now known to also modulate innate and adaptive immunity and suppress proliferation of cancer cells. While much has been revealed about IFN-I, it remains a mystery as to why there are 16 different IFN-I gene products, including IFNβ, IFNω, and 12 subtypes of IFNα. Here, we discuss shared and...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cytokine Signaling Pathways and Interactions
Share to interferon and immune responses
Share to Systemic Lupus Erythematosus Research

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Source

Identifiers

PMID: 33542718
DOI: 10.3389/fimmu.2020.605673

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 24 Oct 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Shared and Unique Features of Human Interferon-Beta and Interferon-Alpha SubtypesPMID 33542718Read ↗

Type I IFN family members: similarity, differences and interaction.Semantic proximity Read ↗

Heterogeneity and functions of the 13 IFN‐α subtypes – lucky for some?Semantic proximity Read ↗

[Review] The Landscape of Interferons in Health and DiseaseSemantic proximity Read ↗

Type I InterferonsSemantic proximity Read ↗

Type I interferons in health and disease: molecular aspects and clinical implicationsSemantic proximity Read ↗

The Role of Structure in the Biology of Interferon SignalingSemantic proximity Read ↗

Interferons, interferon‐like cytokines, and their receptorsSemantic proximity Read ↗

Diversity and relatedness among the type I interferons.Semantic proximity Read ↗

Interferon at 50: new molecules, new potential, new (and old) questions.Semantic proximity Read ↗

Human type-I interferon omega holds potent antiviral properties and promotes cytolytic CD8 <sup>+</sup> T cell responsesSemantic proximity Read ↗

New and atypical families of type I interferons in mammals: comparative functions, structures, and evolutionary relationships.Semantic proximity Read ↗

Interferons and viral infectionsSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.