Article

SARS-COV-2 nucleocapsid protein hijacks multiple components of the host nuclear transport machinery for distinct functions

2024-08-09

Abstract excerpt

Many viruses target the host nuclear transport machinery to traffic their own proteins or restrict trafficking of host cargo, including mediators of antiviral immune signalling. Nucleocapsid (N) proteins from several coronaviruses traffic to the nucleus/nucleolus, with roles in cell cycle regulation. While N-protein from severe acute respiratory syndrome virus 2 (SARS-COV-2), the causative agent of the global COVI...

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Literature Corpus work: 3a431142-d3c4-5ac3-85ac-cb9d4d770b94
DOI: 10.1101/2024.08.09.607288

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