Article

Dengue virus NS1 undergoes partial nuclear translocation to modulate host transcription and support viral replication

2026-04-14

Abstract excerpt

The dengue virus (DENV) non-structural protein 1 (NS1) is a glycoprotein highly conserved among mosquito-borne orthoflaviviruses. NS1 is typically localized in the lumen of the endoplasmic reticulum, where it forms part of the replication complexes, and is also exposed at the plasma membrane. In addition, NS1 is secreted as a lipoprotein. Here, using a combination of approaches, including confocal microscopy with...

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Literature Corpus work: 0a786335-aaf4-5793-beb2-6d906bc73dbd
DOI: 10.64898/2026.04.13.718202

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