Role of IL-1β rs1143634 (+3954C>T) polymorphism in cancer risk: an updated meta-analysis and trial sequential analysis.

doi:10.1177/03000605211060144

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Article

Role of IL-1β rs1143634 (+3954C>T) polymorphism in cancer risk: an updated meta-analysis and trial sequential analysis.

The Journal of international medical research - 1 Dec 2021

Jafrin Sarah, Aziz Md Abdul, Islam Mohammad Safiqul

Abstract excerpt

OBJECTIVE: Oxidative stress caused by the pro-inflammatory cytokine interleukin (IL)-1β has been widely investigated for cancer risk. In this study, we focused on the role of IL-1β rs1143634 polymorphism to reveal its impact on cancer development. METHODS: Related studies with fixed inclusion criteria were selected from electronic databases to May 2021. This meta-analysis was performed with odds ratios and 95%...

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PMID: 34861128
DOI: 10.1177/03000605211060144
PMCID: PMC8647244

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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