Article

An atlas of gene programs in non-small cell lung cancer delineates novel patterns of lineage vacillation, plasticity, and aggressiveness

2025-05-10

Abstract excerpt

Combinations of molecular programs can be altered in cancer cells and contribute to tumor initiation and aggressiveness. We developed a novel framework called a Gene Program Association Study (GPAS) to create an atlas of gene co-expression modules in cancer cells from 127 primary non-small-cell-lung cancers (NSCLCs) and determine their association with clinical and histopathological features. Lung adenocarcinoma (...

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Literature Corpus work: 3a2c8d2a-fd32-5ac7-9cb4-97a94db247ce
DOI: 10.1101/2025.05.06.652317

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