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SPP1+ tumor-associated macrophages induce radioresistance of nasopharyngeal carcinoma through crosstalk with the tumor microenvironment

2024-10-28

Abstract excerpt

The function and phenotype of tumor-associated macrophages (TAMs) influence the efficacy of radiotherapy. However, the effect of different subsets of TAMs on the radioresistance in nasopharyngeal carcinoma (NPC) still needs to be further explored. This study utilized single-cell RNA sequencing (scRNA-seq) to analyze 120,579 cells obtained from 15 NPC samples. Cell annotation, cell‒cell communication analysis, and...

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Literature Corpus work
3a280428-c8d6-520f-83ee-b24b0439c860
DOI
10.1101/2024.10.23.619837
Open publication

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SPP1+ tumor-associated macrophages induce radioresistance of nasopharyngeal carcinoma through crosstalk with the tumor microenvironmentDOI 10.1101/2024.10.23.619837
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