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Whole Genome Sequencing of <i>Plasmodium vivax</i> Isolates Reveals Frequent Sequence and Structural Polymorphisms in Erythrocyte Binding Genes

2020-03-23

Abstract excerpt

Plasmodium vivax malaria is much less common in Africa than the rest of the world because the parasite relies primarily on the Duffy antigen/chemokine receptor ( DARC ) to invade human erythrocytes, and the majority of Africans are Duffy negative. Recently, there has been a dramatic increase in the reporting of P. vivax cases in Africa, with a high number of them being in Duffy negative individuals, potentially...

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Literature Corpus work
3a216636-74b4-575b-9c19-e09ecb470f83
DOI
10.1101/2020.03.23.003293
Open publication

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Whole Genome Sequencing of <i>Plasmodium vivax</i> Isolates Reveals Frequent Sequence and Structural Polymorphisms in Erythrocyte Binding GenesDOI 10.1101/2020.03.23.003293
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