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Article

Genetic differentiation of Plasmodium vivax duffy binding protein in Ethiopia and comparison with other geographical isolates.

Malaria journal - 23 Feb 2024

Abebe Abnet, Dieng Cheikh Cambel, Dugassa Sisay, Abera Deriba, Shenkutie Tassew T, Assefa Ashenafi, Menard Didier, Lo Eugenia, Golassa Lemu

Abstract excerpt

BACKGROUND: Plasmodium vivax Duffy binding protein (PvDBP) is a merozoite surface protein located in the micronemes of P. vivax. The invasion of human reticulocytes by P. vivax merozoites depends on the parasite DBP binding domain engaging Duffy Antigen Receptor for Chemokine (DARC) on these red blood cells (RBCs). PvDBPII shows high genetic diversity which is a major challenge to its use in the development of a...

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Identifiers

PMID: 38395885
DOI: 10.1186/s12936-024-04887-1
PMCID: PMC10885561

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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