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Copy number variations of <i>Plasmodium vivax DBP1</i> , <i>EBP/DBP2</i> , and <i>RBP2b</i> in Duffy-positive and Duffy-negative Ethiopians

2024-05-01

Abstract excerpt

Recent evidence challenges the belief that Duffy-negative individuals are resistant to Plasmodium vivax due to lacking Duffy Antigen Receptor for Chemokines (DARC). Erythrocyte Binding Protein (EBP/DBP2) has shown moderate binding to Duffy-negative erythrocytes in vitro . Reticulocyte Binding Protein 2b (RBP2b) interactions with Transferrin Receptor 1 (TfR1) suggest involvement in Duffy-negative infections. Gene...

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Literature Corpus work
55d744ad-aa2d-5d75-ad38-f60bf731e7df
DOI
10.1101/2024.04.29.591731
Open publication

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Copy number variations of <i>Plasmodium vivax DBP1</i> , <i>EBP/DBP2</i> , and <i>RBP2b</i> in Duffy-positive and Duffy-negative EthiopiansDOI 10.1101/2024.04.29.591731
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