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Potential hidden<i>Plasmodium vivax</i>malaria reservoirs from low parasitemia Duffy-negative Ethiopians: molecular evidence

2023-04-26

Abstract excerpt

<h4>Background</h4> The interaction between the Plasmodium vivax Duffy-binding protein and the corresponding Duffy Antigen Receptor for Chemokines (DARC) is primarily responsible for the invasion of reticulocytes by P. vivax . The Duffy-negative host phenotype, highly prevalent in sub-Saharan Africa, is caused by a single point mutation in the GATA-1 transcription factor binding site of the DARC gene promoter. The...

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Literature Corpus work
6f77e63b-87ed-5d1b-bcbc-7f10c4bbc0df
DOI
10.1101/2023.04.24.23289013
Open publication

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Potential hidden<i>Plasmodium vivax</i>malaria reservoirs from low parasitemia Duffy-negative Ethiopians: molecular evidenceDOI 10.1101/2023.04.24.23289013
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