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Comparative transcriptomics reveal differential gene expression in <i>Plasmodium vivax</i> geographical isolates and implications on erythrocyte invasion mechanisms

2023-02-16

Abstract excerpt

Plasmodium vivax uses Duffy binding protein (PvDBP1) to bind to the Duffy Antigen-Chemokine Receptor (DARC) to invade human erythrocytes. Individuals who lack DARC expression (Duffy-negative) are thought to be resistance to P. vivax . In recent years, P. vivax malaria is becoming more prevalent in Africa with a portion of these cases detected in Duffy-negatives. Apart from DBP1, members of the reticulocyte bindi...

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Literature Corpus work
3b89eb71-22df-51ba-8093-2d0548239ec7
DOI
10.1101/2023.02.16.528793
Open publication

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Comparative transcriptomics reveal differential gene expression in <i>Plasmodium vivax</i> geographical isolates and implications on erythrocyte invasion mechanismsDOI 10.1101/2023.02.16.528793
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