Article
Contrasting epidemiology and genetic variation of Plasmodium vivax infecting Duffy-negative individuals across Africa.
International journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases - 1 Jul 2021
Lo Eugenia, Russo Gianluca, Pestana Kareen, Kepple Daniel, Abagero Beka Raya, Dongho Ghyslaine Bruna Djeunang, Gunalan Karthigayan, Miller Louis H, Hamid Muzamil Mahdi Abdel, Yewhalaw Delenasaw, Paganotti Giacomo Maria
Abstract excerpt
OBJECTIVES: Plasmodium vivax malaria was thought to be rare in Africans who lack the Duffy blood group antigen expression. However, recent studies indicate that P. vivax can infect Duffy-negative individuals and has spread into areas of high Duffy negativity across Africa. Our study compared epidemiological and genetic features of P. vivax between African regions. METHODS: A standardized approach was used to...
Topics
- Duffy Blood-Group System
- Genetic Variation
- Humans
- Malaria, Vivax
- Plasmodium vivax
- Receptors, Cell Surface
- Sudan