Article

Association of Y-chromosomal gr/gr deletions with testicular germ cell tumor: whole-genome analysis of 198,306 individuals

2026-02-05

Abstract excerpt

<h4>Purpose</h4> Germline deletions affecting the Y-chromosomal gr/gr region were reported in 2005 as associated with susceptibility to testicular germ cell tumor (TGCT), a highly heritable tumor type that is the most common cancer type affecting adult men under the age of 45. Attempts to replicate this association have been equivocal, primarily due to limited power. <h4>Methods</h4> Here, we compare and validat...

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Literature Corpus work: 3a1de774-aea4-5984-9d8c-bbdafc5b627d
DOI: 10.64898/2026.02.04.26345360

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