Article

High throughput genome-wide single cell protein:DNA binding site mapping by targeted insertion of promoters (TIP-seq)

2021-03-19

Abstract excerpt

<h4>ABSTRACT</h4> Assessing cell to cell, and importantly, chromosome to chromosome, heterogeneity in cellular phenotypes is a central goal of modern cell biology. However, chromatin profiling in single cells has been extremely challenging, and single chromosome profiling has not been achieved. In cases where single cell methods have shown promise, success has been mainly limited to histone proteins and/or requir...

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Literature Corpus work: 598f807e-0d85-5533-97ed-c20496ddd044
DOI: 10.1101/2021.03.17.435909

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